TR mechanism of action: effects on endocrine function and insulin resistance in patients with type 2 diabetes. TR is a novel glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 (GLP-1) receptor agonist approved in the United States as an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes. It is under investigation for use in chronic weight management, major adverse cardiovascular events, and the management of other conditions, including heart failure with preserved ejection fraction, obesity, and non-cirrhotic non-alcoholic steatohepatitis. The Phase 3 SURPASS 1-5 clinical trial programme was designed to assess the efficacy and safety of once-weekly subcutaneously injected TR (5, 10, and 15 mg), as monotherapy or combination therapy, across a broad spectrum of people with type 2 diabetes.
Use of TR in clinical studies was associated with marked reductions in glycated haemoglobin (-1.87 to -2.59%, -20 to -28 mmol/mol) and body weight (-6.2 to -12.9 kg), as well as reductions in parameters commonly associated with heightened cardiometabolic risk such as blood pressure, visceral adiposity, and circulating triglycerides. In SURPASS-2, these reductions were greater than those with the GLP-1 receptor agonist se 1 mg. TR was well tolerated, with a low risk of hypoglycaemia when used without insulin or insulin secretagogues, and showed a generally similar safety profile to the GLP-1 receptor agonist class. Accordingly, evidence from these clinical trials suggests that tr offers a new opportunity for the effective lowering of glycated haemoglobin and body weight in adults with type 2 diabetes.
◊製品の展示
◊分析レポート
◊お客様の声
◊工場紹介
Zhengzhou Longjia Electronic Technology Co., Ltd. is a professional pharmaceutical science and technology company, dedicated to the research, development, production and sales of peptides, pharmaceutical raw materials and fine chemical intermediates. In terms of product quality control, our company adheres to a strict quality management system. From raw material procurement, production process to product inspection, each link is strictly controlled to ensure the high quality and stability of our products. As a company facing the global market, our products are exported to many countries and regions, and have won wide praise and trust from customers. We always adhere to the principle of ‘quality first, customer first’, and take customers as the centre to provide personalized product customization and solutions to meet customers’ different needs.
Our range of slimming peptides is the result of years of extensive research and collaboration with leading scientists in the field of biochemistry. By utilizing the latest advances in peptide therapy and cutting-edge manufacturing technologies, we have been able to create products that deliver real, measurable results.
In addition to their effectiveness, Longjia′s peptides are formulated with the highest standards of safety and purity. We employ rigorous testing and quality control processes to ensure that every product we offer is of the highest quality. All of our peptides are manufactured in state-of-the-art facilities that comply with international standards, and our production processes adhere to strict quality assurance protocols.
If you′re looking for a reliable and effective solution to support your weight management journey, Zhengzhou Longjia Electronic Technology Co., Ltd. is your trusted partner. Contact us today to learn more about our products and how they can help you achieve your goals.
◊梱包と輸送
◊私たちの強み
High quality, competitive price, adequate stock and fast delivery competitive price.
1. Enterprise standard and 99% purity.
2. Exclusive one-to-one customer service, any inquiries will be replied within 12 hours.
3. Safe and fast shipping, about 7-15 days to your address.
4. Tracking number provided to you after ordering, keep tracking goods and update information to you until the goods arrive safely at your address.
5. OEM service, redesign label, packing box as customer’s requirement. Add customer’s logo.
6. Excellent after-sale service.
◊よくある質問
Q1:How is the product quality?
A:Pharmaceutical raw material products strictly select raw materials. We guarantee that the concentration of each box of product is higher than 99%. Support third-party testing, if the test does not meet the standard, we will replace the product for free or support the refund.
Q2: Do you provide samples?
A:Yes, we provide samples for free.
Q3:Is there any discount
A:Yes, for larger quantity, we always support with better price.
Q4:What payment terms do you accept?
A:We accept Bank Transfer, Wise, PayPal, Western Union, Bitcoin and USDT etc.
Q5: When can I receive the goods after payment?
A: Depending on your location
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
or mass order, please allow 5-15 days by Air, 20-35 days by Sea.
Q6:How do you treat quality complaint?
A:First of all, our quality control will ensure the product quality in advance. If there is a real quality problem caused by us, we will send you free goods for replacement or refund.